Scripps Research Institute Scientists Reveal How Deadly Ebola Virus Assembles

Scientists at The Scripps Research Institute (TSRI) have discovered the molecular mechanism by which the deadly Ebola virus assembles, providing potential new drug targets. Surprisingly, the study showed that the same molecule that assembles and releases new viruses also rearranges itself into different shapes, with each shape controlling a different step of the virus’s life cycle.

“Like a ‘Transformer’, this protein of the Ebola virus adopts different shapes for different functions,” said Erica Ollmann Saphire, Ph.D., professor in the Department of Immunology and Microbial Science at TSRI. “It revises a central dogma of molecular biology—that a protein molecule has one shape that predestines one biological function.”



There is no possibility that the Ebola virus is man made. We do not have the technology to design the genes necessary to transform the shape of the virus to accommodate new functionality in different phases of its life style.

So the first question to ask is what will we do when this disease comes here? And then we have to ask why the pResident has opened our southern border to everyone at this time?

David DeGerolamo

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