A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
Although public health measures were able to stop the SARS-CoV outbreak4, recent metagenomics studies have identified sequences of closely related SARS-like viruses circulating in Chinese bat populations that may pose a future threat1. However, sequence data alone provides minimal insights to identify and prepare for future prepandemic viruses. Therefore, to examine the emergence potential (that is, the potential to infect humans) of circulating bat CoVs, we built a chimeric virus encoding a novel, zoonotic CoV spike protein—from the RsSHC014-CoV sequence that was isolated from Chinese horseshoe bats1—in the context of the SARS-CoV mouse adapted backbone. The hybrid virus allowed us to evaluate the ability of the novel spike protein to cause disease independently of other necessary adaptive mutations in its natural backbone. Using this approach, we characterized CoV infection mediated by the SHC014 spike protein in primary human airway cells and in vivo, and tested the efficacy of available immune therapeutics against SHC014-CoV. Together, the strategy translates metagenomics data to help predict and prepare for future emergent viruses.
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I do know that the government shut down this lab at UNC-CH due to the danger it posed. I do know that Dr. Fauci funded its continued research in Wuhan with our tax dollars.
Just to be clear:
So they created the SARS-COV-2 variant:
[The mouse] hybrid virus allowed us to evaluate the ability of the novel spike protein to cause disease independently of other necessary adaptive mutations in its natural backbone.
I do not know what other abilities that the Wuhan lab inserted into this “novel” virus other than to note that it has the ability to infect our immune cells using a different pathway than what this 2015 paper outlined.
So the question is: what are the consequences of creating a biological weapon since their research did not create a vaccine? Their research only led to the addition of more “abilities” to create this pandemic. What are the consequences of worldwide genocide? Why are there no calls for an international treaty to stop further “research”?
David DeGerolamo
h/t Peggy
I believe that there was a recent blog or two about the subject of what the Wuhan “researchers” did and that is they spliced a PRRA furin cleavage site gene sequence into a bat (or possibly a pangolin) virus. This is not a mutation effect, but different science all together. It’s the virus’ force multiplier.
As to why are there no outcries as to China creating a bio weapon? That is a really good question. I know that I have said that the repercussions need to be severe as in returning China to the stone age and removing them from ever seeing “world power” status again. Outlawing such “research” would not be sufficient as China routinely demonstrates that it doesn’t give two shits about other nation’s or even international law.
What’s also very concerning is the amount of disinformation that has been spread, especially early on, by our so called experts to attempt to deny and “disprove”, though they have not done so, that this is anything other than a naturally occurring mutation.